Marker for colorectal cancer and application of marker
The invention relates to a marker for a colorectal cancer and an application of the marker, and in particular relates to abnormal expression of a GTF2H5 gene of the marker for the colorectal cancer, adetection method of the colorectal cancer and an application of the marker. The marker for the color...
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| creator | SHUAI DIQUAN TAN HUIBIAO SHENG SITONG LI YANPENG WANG YUN XU TE |
| description | The invention relates to a marker for a colorectal cancer and an application of the marker, and in particular relates to abnormal expression of a GTF2H5 gene of the marker for the colorectal cancer, adetection method of the colorectal cancer and an application of the marker. The marker for the colorectal cancer includes a GTF2H5 gene abnormally expressed nucleic acid or/and proteins, and can realize test of GTF2H5 gene abnormality, nucleic acid or/and protein expression by using a gene sequencing technology, a chip semi-quantitative detection technology, a qPCR quantitative detection technology, a Western blotting semi-quantitative detection technology, an immunohistochemical staining technology, an in-situ hybridization technology and a liquid biopsy technology, and the test has better accuracy, stronger specificity and higher sensitivity.
本发明涉及一种结直肠癌标志物及其应用，具体涉及一种结直肠癌标志物GTF2H5基因的异常表达及其检测方法和应用，所述结直肠癌标志物包括GTF2H5基因异常表达的核酸或/和蛋白质，并通过运用基因测序技术、芯片半定量检测技术、qPCR定量检测技术、蛋白印迹半定量检测技术、免疫组织化学染色技术、原位杂交技术和液体活检技术能够实现GTF2H5基因异常 |
| format | Patent |
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本发明涉及一种结直肠癌标志物及其应用，具体涉及一种结直肠癌标志物GTF2H5基因的异常表达及其检测方法和应用，所述结直肠癌标志物包括GTF2H5基因异常表达的核酸或/和蛋白质，并通过运用基因测序技术、芯片半定量检测技术、qPCR定量检测技术、蛋白印迹半定量检测技术、免疫组织化学染色技术、原位杂交技术和液体活检技术能够实现GTF2H5基因异常</description><language>chi ; eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; ENZYMOLOGY ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; PHYSICS ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200310&DB=EPODOC&CC=CN&NR=110872625A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200310&DB=EPODOC&CC=CN&NR=110872625A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SHUAI DIQUAN</creatorcontrib><creatorcontrib>TAN HUIBIAO</creatorcontrib><creatorcontrib>SHENG SITONG</creatorcontrib><creatorcontrib>LI YANPENG</creatorcontrib><creatorcontrib>WANG YUN</creatorcontrib><creatorcontrib>XU TE</creatorcontrib><title>Marker for colorectal cancer and application of marker</title><description>The invention relates to a marker for a colorectal cancer and an application of the marker, and in particular relates to abnormal expression of a GTF2H5 gene of the marker for the colorectal cancer, adetection method of the colorectal cancer and an application of the marker. The marker for the colorectal cancer includes a GTF2H5 gene abnormally expressed nucleic acid or/and proteins, and can realize test of GTF2H5 gene abnormality, nucleic acid or/and protein expression by using a gene sequencing technology, a chip semi-quantitative detection technology, a qPCR quantitative detection technology, a Western blotting semi-quantitative detection technology, an immunohistochemical staining technology, an in-situ hybridization technology and a liquid biopsy technology, and the test has better accuracy, stronger specificity and higher sensitivity.
本发明涉及一种结直肠癌标志物及其应用，具体涉及一种结直肠癌标志物GTF2H5基因的异常表达及其检测方法和应用，所述结直肠癌标志物包括GTF2H5基因异常表达的核酸或/和蛋白质，并通过运用基因测序技术、芯片半定量检测技术、qPCR定量检测技术、蛋白印迹半定量检测技术、免疫组织化学染色技术、原位杂交技术和液体活检技术能够实现GTF2H5基因异常</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>ENZYMOLOGY</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PHYSICS</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>SPIRITS</subject><subject>TESTING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDDzTSzKTi1SSMsvUkjOz8kvSk0uScxRSE7MSwaKJualKCQWFORkJieWZObnKeSnKeSC1fMwsKYl5hSn8kJpbgZFN9cQZw_d1IL8-NTigsTk1LzUknhnP0NDAwtzIzMjU0djYtQAAIVyLVg</recordid><startdate>20200310</startdate><enddate>20200310</enddate><creator>SHUAI DIQUAN</creator><creator>TAN HUIBIAO</creator><creator>SHENG SITONG</creator><creator>LI YANPENG</creator><creator>WANG YUN</creator><creator>XU TE</creator><scope>EVB</scope></search><sort><creationdate>20200310</creationdate><title>Marker for colorectal cancer and application of marker</title><author>SHUAI DIQUAN ; TAN HUIBIAO ; SHENG SITONG ; LI YANPENG ; WANG YUN ; XU TE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN110872625A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2020</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>ENZYMOLOGY</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PHYSICS</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>SPIRITS</topic><topic>TESTING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>SHUAI DIQUAN</creatorcontrib><creatorcontrib>TAN HUIBIAO</creatorcontrib><creatorcontrib>SHENG SITONG</creatorcontrib><creatorcontrib>LI YANPENG</creatorcontrib><creatorcontrib>WANG YUN</creatorcontrib><creatorcontrib>XU TE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SHUAI DIQUAN</au><au>TAN HUIBIAO</au><au>SHENG SITONG</au><au>LI YANPENG</au><au>WANG YUN</au><au>XU TE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Marker for colorectal cancer and application of marker</title><date>2020-03-10</date><risdate>2020</risdate><abstract>The invention relates to a marker for a colorectal cancer and an application of the marker, and in particular relates to abnormal expression of a GTF2H5 gene of the marker for the colorectal cancer, adetection method of the colorectal cancer and an application of the marker. The marker for the colorectal cancer includes a GTF2H5 gene abnormally expressed nucleic acid or/and proteins, and can realize test of GTF2H5 gene abnormality, nucleic acid or/and protein expression by using a gene sequencing technology, a chip semi-quantitative detection technology, a qPCR quantitative detection technology, a Western blotting semi-quantitative detection technology, an immunohistochemical staining technology, an in-situ hybridization technology and a liquid biopsy technology, and the test has better accuracy, stronger specificity and higher sensitivity.
本发明涉及一种结直肠癌标志物及其应用，具体涉及一种结直肠癌标志物GTF2H5基因的异常表达及其检测方法和应用，所述结直肠癌标志物包括GTF2H5基因异常表达的核酸或/和蛋白质，并通过运用基因测序技术、芯片半定量检测技术、qPCR定量检测技术、蛋白印迹半定量检测技术、免疫组织化学染色技术、原位杂交技术和液体活检技术能够实现GTF2H5基因异常</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE |
| title | Marker for colorectal cancer and application of marker |
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