Compositions and methods for the display of proteins on the surface of bacteria and their derived vesicles and uses thereof

The invention relates to compositions and methods for the display of proteins on the surface of bacteria and their derived vesicles and uses thereof. The present invention relates to compositions andmethods for displaying proteins and polypeptides on the surface of cells and cellular vesicles. Methods and compositions for drug and vaccine delivery using cell surface display systems of the presentinvention are also disclosed. 本发明涉及蛋白质在细菌及其衍生小泡表面展示的组合物和方法及其用途。本发明涉及用于在细胞表面和细胞小泡表面展示蛋白质和多肽的组合物和方法。本文还公开了利用本发明的细胞表面展示系统用于递送药物和疫苗的方法和组合物。