Indole fluorescent probe and preparation method and application thereof

The application belongs to the technical field of biomedicine, and particularly relates to an indole fluorescent probe and a preparation method and application thereof. The application provides the indole fluorescent probe, and a chemical formula of the probe is shown in a formula I in the specifica...

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Hauptverfasser:	HU MENGMENG, LIU QIFA, LI YOU, HU JINRONG, ZHOU WEI, ZANG XIAOHAO
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM ADHESIVES CHEMISTRY DYES HETEROCYCLIC COMPOUNDS INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FORELSEWHERE MEASURING METALLURGY MISCELLANEOUS APPLICATIONS OF MATERIALS MISCELLANEOUS COMPOSITIONS NATURAL RESINS ORGANIC CHEMISTRY PAINTS PHYSICS POLISHES TESTING
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Beschreibung
Zusammenfassung:	The application belongs to the technical field of biomedicine, and particularly relates to an indole fluorescent probe and a preparation method and application thereof. The application provides the indole fluorescent probe, and a chemical formula of the probe is shown in a formula I in the specification, wherein R1 is selected from H or Cl; R2 is selected from fluorescent molecules; and n is an integer of 2-8. The application provides the indole fluorescent probe and the preparation method and application thereof, the interference of autofluorescence of an organism can be eliminated, and the TSPO content in the organism is efficiently and accurately detected. 本申请属于生物医药的技术领域，尤其涉及一种吲哚荧光探针及其制备方法和应用。本申请提供了一种吲哚荧光探针，其化学式如式Ⅰ所示，其中，R选自H或Cl；R选自荧光分子；n为2-8的整数。本申请提供了一种吲哚荧光探针及其制备方法和应用，能排除生物体自发荧光的干扰，高效的、准确的在生物体中检测TSPO含量。