Preparation method of adsorbent used for refining of penicillin fermentation broth

The invention relates to the field of preparation of microbial fermentation products, in particular to a preparation method of an adsorbent used for refining of penicillin fermentation broth. According to the preparation method, a porous melamine resin microsphere is prepared and is then subjected t...

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Bibliographische Detailangaben
Hauptverfasser: ZHOU ZHENZHEN, ZHU RUNDONG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to the field of preparation of microbial fermentation products, in particular to a preparation method of an adsorbent used for refining of penicillin fermentation broth. According to the preparation method, a porous melamine resin microsphere is prepared and is then subjected to surface modification by a microporous surface modifier so as to prepare the adsorbent used for refining of the penicillin fermentation broth. The adsorbent can enrich an effective component, namely penicillin in a low-titer filtrate generated in the production process of penicillin and then desorbthe effective component penicillin in an acidic solution to achieve the purpose of refining penicillin. The microporous surface modifier used in the invention contains a large number of lactam groups, so the adsorbent has good nucleophilicity to the beta-lactam antibiotic penicillin, and has the advantages of efficient adsorption performance, good enrichment effect and good recycling effect. 本发明涉及微生物发酵产品制备领域,具体关于一种青霉素发酵液