Cancer suppressor gene and application thereof

The invention discloses a diagnosis and treatment marker for nasopharyngeal carcinoma. The marker is VILL, experiments show that the expression of the VILL and a protein thereof is significantly reduced in nasopharyngeal carcinoma tissue and suggest that the VILL can be used in the diagnosis or trea...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	ZHANG JIANPING, WEN YUETING, PAN XINGHUA, HUANG ZHONGXI, SHEN WEIXI
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The invention discloses a diagnosis and treatment marker for nasopharyngeal carcinoma. The marker is VILL, experiments show that the expression of the VILL and a protein thereof is significantly reduced in nasopharyngeal carcinoma tissue and suggest that the VILL can be used in the diagnosis or treatment of the nasopharyngeal carcinoma. Further, in-vitro cell experiments confirm that the VILL is related to the proliferation, apoptosis, migration, and invasion of nasopharyngeal carcinoma cells and suggest that the VILL can be used as a drug target in the clinical treatment of the nasopharyngealcarcinoma. The invention also discloses the protein EIF3J interacting with a VILL gene. Experiments find that the EIF3J is positively correlated with the VILL and suggest that the expression level ofthe VILL gene can be increased through the EIF3J, so that the purpose of treating the nasopharyngeal carcinoma or nasopharyngeal carcinoma metastasis is achieved, and a novel treatment idea is provided. 本发明公开了鼻咽癌的诊治标志物，所述标志物为