Method for improving storage stability of ketorolac tromethamine injection

The invention belongs to the technical field of pharmaceutical preparations, and particularly relates to a method for improving storage stability of a ketorolac tromethamine injection. The prepared ketorolac tromethamine injection is filled into a polypropylene plastic ampoule or a cycloolefin polym...

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Hauptverfasser: QIN SHIHUI, HAO GUIZHOU
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention belongs to the technical field of pharmaceutical preparations, and particularly relates to a method for improving storage stability of a ketorolac tromethamine injection. The prepared ketorolac tromethamine injection is filled into a polypropylene plastic ampoule or a cycloolefin polymer plastic bottle, so that the problem that visible foreign matters are unqualified due to the factthat the injection easily generates white dots in the long-term placement process of the ketorolac tromethamine injection is solved, insoluble particles are few, and the quality is stable. 本发明属于医药制剂技术领域,具体涉及一种提高酮咯酸氨丁三醇注射液存储稳定性的方法。本发明将制备好的酮咯酸氨丁三醇注射液灌装于聚丙烯塑料安瓿或环烯烃聚合物塑料瓶中,解决了酮咯酸氨丁三醇注射液长期放置过程中注射液容易产生白色小点,从而导致可见异物不合格的问题,不溶性微粒较少,质量稳定。