Application of benzil monohydrazon-1-naphthaldehyde schiff base

The invention relates to the fields of medicinal chemistry and functional materials, in particular to application of schiff base formed by benzoyl dihydrazone or benzoyl monohydrazone with 1-naphthaldehyde through a reaction to anticancer and antibacterial drugs, medical materials, functional materi...

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Bibliographische Detailangaben
Hauptverfasser: XING DIANXIANG, LIU SHUAI, TAN XUEJIE
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention relates to the fields of medicinal chemistry and functional materials, in particular to application of schiff base formed by benzoyl dihydrazone or benzoyl monohydrazone with 1-naphthaldehyde through a reaction to anticancer and antibacterial drugs, medical materials, functional materials and other fields. Benzoyl dihydrazone-N,N'-bis(1-formyl naphthalene) is a pale yellow shuttle-like crystal in appearance with a melting point of 201.0-203.0 DEG C and the molecular formula of C36H26N4; and benzoyl monohydrazone-N-1-formyl naphthalene is a yellow lumpy crystal in appearance witha melting point of 135.2-136.7 DEG C and a molecular formula of C25H18N2O. The structures of the benzoyl dihydrazone-N, N'-bis(1-formyl naphthalene) and the benzoyl monohydrazone-N-1-formyl naphthalene are shown in the specifications. The two substances have certain inhibitory activity on lung cancer cells, breast cancer cells, escherichia coli and staphylococcus aureus and can be used in the antitumor and antibacterial d