Buparvaquone preparation method

The invention provides a buparvaquone preparation method, which comprises: carrying out condensation, hydrolysis and decarboxylation by using o-phthalic acid diester and 2-(4-tert-butylcyclohexylmethyl)succinic acid diester as a raw material to prepare 2-[(4-tert-butylcyclohexyl)methyl]-2,3-dihydro-1,4-naphthalenedione, carrying out a substitution reaction on the 2-[(4-tert-butylcyclohexyl)methyl]-2,3-dihydro-1,4-naphthalenedione and a halogenating reagent to obtain a dihalogenated compound mixture, removing halogen hydride through an elimination reaction to obtain 2-[(4-tert-butylcyclohexyl)methyl]-3-halo-1,4-naphthalenedione, and finally carrying out a hydrolysis reaction to obtain the buparvaquone (I). According to the invention, the method has advantages of cheap and easily available raw materials, safe and simple process operation, low cost, little wastewater generation, safety and environmental protection, easily achieved reaction conditions, stable reaction intermediate, high reaction activity, high se