Halofuginone hydrobromide soluble powder and preparation method thereof

The invention belongs to the technical field of pharmaceutical preparations and discloses a halofuginone hydrobromide soluble powder and a preparation method thereof. The halofuginone hydrobromide soluble powder is prepared from the following raw materials in percentage by weight: 0.6-2% of halofugi...

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Hauptverfasser: GAO GUICHAO, LI LINGFENG, HAO XIAOQIAN, CUI JUNYA, LUO XIANYANG, ZHAO SHUOLEI, HU SHUAI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the technical field of pharmaceutical preparations and discloses a halofuginone hydrobromide soluble powder and a preparation method thereof. The halofuginone hydrobromide soluble powder is prepared from the following raw materials in percentage by weight: 0.6-2% of halofuginone hydrobromide, 2.0-30.0% of emulsifying agent, 1.0-20.0% of cosurfactant and 50.0-90.0% of soluble solid adsorption material. The preparation method comprises the steps: uniformly mixing halofuginone hydrobromide, the emulsifying agent and the cosurfactant at 40-70 DEG C, processing the mixtureby using a colloid mill, and cooling the mixture to the room temperature to obtain a halofuginone hydrobromide self-emulsifying concentrate; smashing a water-soluble solid adsorption material, and then, uniformly mixing the smashed water-soluble solid adsorption material with the halofuginone hydrobromide self-emulsifying concentrate to obtain a semisolid; drying the semisolid, then, smashing thesemisolid to obtain the ha