Compound preparation valsartan amlodipine tablet and preparation method thereof

The present invention provides a compound preparation valsartan amlodipine tablet and a preparation method thereof. The compound preparation comprises a plain tablet and a film coating layer. The plain tablet comprises main medicines and auxiliary materials, the main medicines comprise valsartan and amlodipine besylate, and the auxiliary materials comprise fillers, disintegrating agents, lubricants and glidants. The preparation method solves a problem that related substances increase due to wet granulation of the variety, thereby affecting safety of drug use. The preparation method also solvesproblems that content is uneven caused by uneven granules by the dry granulation technology and batch-to-batch quality differences are excessively large caused by uneven granules caused by uneven dissolution rate. The preparation method solves a problem of degradation of the preparation due to hygroscopicity and improves stability of the product. 本发明提供了一种复方制剂缬沙坦氨氯地平片及其制备方法，本发明中的复方制剂包括素片、薄膜衣层。素片包括主药和辅料，主药包括缬沙坦、苯磺酸氨氯地平，辅料包