Drug sustained-release carrier and preparation method and application thereof

The invention discloses a ganoderma spore microsphere drug sustained-release carrier. Ganoderma spore microspheres are elliptical spheres, the size is (4-8)x(6-10) [mu]m, and the outer wall aperture is 230-350 nm. The preparation method of the ganoderma spore microsphere drug sustained-release carrier comprises the following steps: (1) ultraviolet irradiation treatment: spreading ganoderma spores,and irradiating the spores by adopting an ultraviolet lamp light source to achieve an embrittlement purpose; (2) degreasing treatment: degreasing the ganoderma spores subjected to ultraviolet irradiation treatment with ethanol to remove lipid substances in the ganoderma spores, filtering the ganoderma spores, performing washing with deionized water, and performing drying; and (3) acid-base treatment: soaking the degreased ganoderma spores in concentrated hydrochloric acid, performing filtering, soaking the spores in a dilute alkali solution, and performing filtering and drying to obtain the finished product. The gano