Propolis nanoparticles, preparation method and application of propolis nanoparticles and preparation method of freeze-dried powder of propolis nanoparticles

The invention discloses a preparation method of propolis nanoparticles. The preparation method of the propolis nanoparticles comprises the steps that a stabilizer is added, a propolis organic phase solution is mixed with an aqueous phase under ultrasonic conditions, then an organic solvent is removed by rotary evaporation under reduced pressure, and the propolis nanoparticles are obtained. According to the preparation method of the propolis nanoparticles, propolis is made into the nanoparticles by nanotechnology, a series of problems such as poor propolis solubility, difficulty in dispersing,difficulty in drug administration and difficulty in further processing of preparations are effectively solved, wherein the difficulty in dispersing, the difficulty in drug administration and the difficulty in further processing of preparations are caused by poor propolis solubility, the application value of the propolis is improved, and good industrialization prospect is achieved. 本发明公开了一种蜂胶纳米粒的制备方法，通过加入稳定剂，并在超声条件下，将蜂胶有机相