Method for synthesizing 2, 4-dichloroaniline by continuous chlorination process

The invention relates to a continuous chlorination method for synthesizing 2, 4-dichlorophenol. The method comprises following steps: mixing acetanilide generated by acetylation of aniline with a certain amount of acetic acid; carrying out continuous chlorination, flash concentration and centrifugal...

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Hauptverfasser: CAO SHENGWEN, LIAO LISHA, LI HUAXUAN, WANG YU
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a continuous chlorination method for synthesizing 2, 4-dichlorophenol. The method comprises following steps: mixing acetanilide generated by acetylation of aniline with a certain amount of acetic acid; carrying out continuous chlorination, flash concentration and centrifugal filtration to obtain 2, 4-dichloroacetanilide, taking 2, 4-dichloroacetanilide as a raw material, and carrying out hydrolyzing under an acidic condition, cooling, crystallizing and filtering to obtain a hydrochloride of 2, 4-dichloroacetanilide, adding water into an obtained filter cake to dilute,adjusting the pH value, filtering, washing with water, and drying to obtain high-purity 2, 4-dichloroacetanilide. Compared with other patent literatures, the method has the advantages that continuouschlorination is realized, the operation is safe, the reaction speed is high, the chlorine loss is low, and the chlorine and the solvent are recycled, so that the conversion rate and purity of the target product are improved, t