Anti-tumor pharmaceutical composition with synergistic effects and application thereof

The invention belongs to the technical field of biological medicines, and relates to a pharmaceutical composition capable of treating cancers; and more specifically, the invention discloses an anti-tumor pharmaceutical composition with synergistic effects and application thereof. By synergistic effe...

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Hauptverfasser: WANG SHAONING, WANG CUNYANG, SONG YANZHI, DENG YIHUI, FU PINGPING, LIU XINRONG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the technical field of biological medicines, and relates to a pharmaceutical composition capable of treating cancers; and more specifically, the invention discloses an anti-tumor pharmaceutical composition with synergistic effects and application thereof. By synergistic effects between drugs, dosages of single drugs in the anti-tumor pharmaceutical composition with the synergistic effects are reduced, so that strong toxic effects of the drugs on cells are overcome; and apoptosis of solid tumor cells is induced by increasing active oxygen levels in the cells. The anti-tumor pharmaceutical composition with the synergistic effects disclosed by the invention consists of arsenic trioxide and cobalt salts, wherein a mole ratio of the arsenic trioxide to the cobalt saltsis (1 to 1) to (1 to 10), and preferably (1 to 2) to (1 to 5). The cobalt salts are cobalt acetate, cobalt chloride, cobalt phosphate, cobalt silicate, cobalt succinate, cobalt fumarate and cobalt sulfate. The anti-tumor phar