Oily injection containing estriol or derivatives thereof

The invention belongs to the technical field of medicine and particularly relates to an oily injection (also named oily drug delivery storage) of estriol (or derivatives thereof) as well as a preparation method of the oily injection. The medicine preparation comprises a main material of the estriol (or derivatives thereof) and auxiliary materials including a solvent, an analgesic, a dispersing agent and an antioxidant. The medicine preparation can locally form a storage after medicine is subcutaneous or intramuscular injection administration in an oily true solution state, and medicine molecules dissolved in the oily solution are then slowly distributed in water-based gaps in bodies and gradually enter blood circulation to play therapeutic effects, so that the medicine can have certain slow-release effect controlled in 2 d or longer. 本发明属于医药技术领域，具体涉及一种雌三醇(或其衍生物)的油性注射剂(又称油性递药贮库)及其制备方法。本发明所述的药物制剂，主药雌三醇(或其衍生物)，辅料可包括溶剂、镇痛剂、分散剂和抗氧化剂，所述的溶剂、镇痛剂、分散剂和抗氧化剂。本发明所述药物制剂是将药物以油性真溶液状态经皮下或肌肉注射给药后会在局部形成贮库，溶解在油性溶液中的药物分子随后缓慢分配进入体