Method for extracting and purifying chlorogenic acid in chrysanthemum buds
The invention discloses a method for extracting and purifying chlorogenic acid in chrysanthemum buds. According to the invention, crushed and sieved chrysanthemum buds are used as a raw material; an ethanol aqueous solution is used as a solvent for ultrasonic extraction; macroporous resin is used fo...
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| creator | REN PING DAI FUCAI |
| description | The invention discloses a method for extracting and purifying chlorogenic acid in chrysanthemum buds. According to the invention, crushed and sieved chrysanthemum buds are used as a raw material; an ethanol aqueous solution is used as a solvent for ultrasonic extraction; macroporous resin is used for primary separation; ethyl acetate/petroleum ether is used for reversed-phase separation; a polyamide resin column is used for purification and separation; and recrystallization is performed to obtain chlorogenic acid. The method provided by the invention has good reproducibility and is suitable for industrial production.
本发明公开了一种提取纯化胎菊中绿原酸的方法。以粉碎过筛后的胎菊为原料，用乙醇水溶液为溶剂进行超声提取，利用大孔树脂初步分离以及利用乙酸乙酯/石油醚反相分离，再利用聚酰胺树脂柱纯化分离，经过重结晶得到绿原酸。本发明的方法重现性好，适合工业化生产。 |
| format | Patent |
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本发明公开了一种提取纯化胎菊中绿原酸的方法。以粉碎过筛后的胎菊为原料，用乙醇水溶液为溶剂进行超声提取，利用大孔树脂初步分离以及利用乙酸乙酯/石油醚反相分离，再利用聚酰胺树脂柱纯化分离，经过重结晶得到绿原酸。本发明的方法重现性好，适合工业化生产。</description><language>chi ; eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20191213&DB=EPODOC&CC=CN&NR=110563584A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20191213&DB=EPODOC&CC=CN&NR=110563584A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>REN PING</creatorcontrib><creatorcontrib>DAI FUCAI</creatorcontrib><title>Method for extracting and purifying chlorogenic acid in chrysanthemum buds</title><description>The invention discloses a method for extracting and purifying chlorogenic acid in chrysanthemum buds. According to the invention, crushed and sieved chrysanthemum buds are used as a raw material; an ethanol aqueous solution is used as a solvent for ultrasonic extraction; macroporous resin is used for primary separation; ethyl acetate/petroleum ether is used for reversed-phase separation; a polyamide resin column is used for purification and separation; and recrystallization is performed to obtain chlorogenic acid. The method provided by the invention has good reproducibility and is suitable for industrial production.
本发明公开了一种提取纯化胎菊中绿原酸的方法。以粉碎过筛后的胎菊为原料，用乙醇水溶液为溶剂进行超声提取，利用大孔树脂初步分离以及利用乙酸乙酯/石油醚反相分离，再利用聚酰胺树脂柱纯化分离，经过重结晶得到绿原酸。本发明的方法重现性好，适合工业化生产。</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPDyTS3JyE9RSMsvUkitKClKTC7JzEtXSMxLUSgoLcpMqwTxkjNy8ovy01PzMpMVEpMzUxQy84BiRZXFiXklGam5pbkKSaUpxTwMrGmJOcWpvFCam0HRzTXE2UM3tSA_PrW4IDE5NS-1JN7Zz9DQwNTM2NTCxNGYGDUASig1bw</recordid><startdate>20191213</startdate><enddate>20191213</enddate><creator>REN PING</creator><creator>DAI FUCAI</creator><scope>EVB</scope></search><sort><creationdate>20191213</creationdate><title>Method for extracting and purifying chlorogenic acid in chrysanthemum buds</title><author>REN PING ; DAI FUCAI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN110563584A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2019</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>REN PING</creatorcontrib><creatorcontrib>DAI FUCAI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>REN PING</au><au>DAI FUCAI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Method for extracting and purifying chlorogenic acid in chrysanthemum buds</title><date>2019-12-13</date><risdate>2019</risdate><abstract>The invention discloses a method for extracting and purifying chlorogenic acid in chrysanthemum buds. According to the invention, crushed and sieved chrysanthemum buds are used as a raw material; an ethanol aqueous solution is used as a solvent for ultrasonic extraction; macroporous resin is used for primary separation; ethyl acetate/petroleum ether is used for reversed-phase separation; a polyamide resin column is used for purification and separation; and recrystallization is performed to obtain chlorogenic acid. The method provided by the invention has good reproducibility and is suitable for industrial production.
本发明公开了一种提取纯化胎菊中绿原酸的方法。以粉碎过筛后的胎菊为原料，用乙醇水溶液为溶剂进行超声提取，利用大孔树脂初步分离以及利用乙酸乙酯/石油醚反相分离，再利用聚酰胺树脂柱纯化分离，经过重结晶得到绿原酸。本发明的方法重现性好，适合工业化生产。</abstract><oa>free_for_read</oa></addata></record> |
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| title | Method for extracting and purifying chlorogenic acid in chrysanthemum buds |
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