Broad-spectrum malassezia-resistant natural product composition and application thereof

The present invention provides a broad-spectrum malassezia-resistant natural product composition. The broad-spectrum malassezia-resistant natural product composition consists of tropolone, cinnamaldehyde and nisin. In-vitro drug sensitivity experiments prove that the tropolone, cinnamaldehyde and ni...

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Hauptverfasser: LYU ZHI, GAN LISHE, GAO YULI, FENG QIPENG, ZHOU CHANGXIN, MO JIANXIA, HONG MINHUA, ZHANG LISHA
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention provides a broad-spectrum malassezia-resistant natural product composition. The broad-spectrum malassezia-resistant natural product composition consists of tropolone, cinnamaldehyde and nisin. In-vitro drug sensitivity experiments prove that the tropolone, cinnamaldehyde and nisin have an obvious inhibition effect on malassezia, besides, the three materials have synergistic or addition effects, so that compounding of the three materials can reduce drug dosage, enhance a sterilization effect and prevent drug resistance. The composition can be made into drugs and daily chemical products which can be used for treating skin diseases caused by malassezia, such as seborrheic dermatitis, dandruff, etc. Compared with synthetic drugs, the natural product composition is strongin micro-organism-inhibiting ability, natural and free of toxicity, stable in property, small in damages to the environment, low in stimulation, obvious in effects, etc., and has wide application prospects. 本发明提供一种广谱抗马拉色菌的天然产