Preparation method of substituted phenylacetonitrile

The invention belongs to the field of medicinal chemistry and chemical synthesis, and particularly relates to a preparation method of a class of substituted phenylacetonitrile compounds (IV). According to the present invention, the preparation method has advantages of mild reaction conditions, simple post-treatment, environmental protection, low production cost, high product purity and high yield,and is suitable for industrial preparation of substituted phenylacetonitrile compounds (IV). 本发明属于药物化学和化学合成领域，具体涉及一类取代苯乙腈化合物(IV)的制备方法。该制备方法反应条件温和、后处理简单、环保、生产成本低、产品纯度高、收率高，适于工业化制备取代苯乙腈化合物(IV)。