Method for preparing trifluoroacetamide by using micro-channel reaction technology

The invention discloses a method for continuously preparing trifluoroacetamide through a reaction of ethyl trifluoroacetate and ammonia gas, wherein raw materials ethyl trifluoroacetate and ammonia gas are subjected to mixing and reaction in a reaction module in a micro-channel reactor, and module quenching is performed to obtain trifluoroacetamide. According to the present invention, the method has advantages of high conversion rate, short reaction time, safe and controllable reaction and continuous industrial amplification. 本发明公开了一种三氟乙酸乙酯与氨气反应连续化制备三氟乙酰胺的方法，在微通道反应器中，原料三氟乙酸乙酯与氨气在反应模块中经混合和反应，并经淬灭模块后得到三氟乙酰胺。发明提供的方法有转化率高、反应时间短、反应安全可控和可以连续化工业放大。