Method for synthesizing azaindoline derivative

The invention discloses a method for synthesizing azaindoline derivatives, and belongs to the technical field of organic synthesis. Pyridine carbon-hydrogen bond activation functionalization is catalyzed by rare earth, so that synthesis of azaindoline derivatives with diversified structures is achieved. Specifically, in a rare earth catalytic system, various alkenyl-substituted aminopyridine is used as a raw material to prepare the azaindoline derivative. The method disclosed by the invention is wide in raw material source or easy to prepare, simple and convenient to operate, controllable in selectivity, high in yield, mild in condition and wide in universality. 本发明公开了一种合成氮杂吲哚啉衍生物的方法，属于有机合成技术领域。本发明通过稀土催化吡啶碳氢键活化官能团化从而实现结构多样化的氮杂吲哚啉衍生物合成。具体是在稀土催化体系下，以各种烯基取代的氨基吡啶为原料，制备氮杂吲哚啉衍生物。本发明方法原料来源广泛或易于制备，操作简便、选择性可控，收率高，条件温和，普适性广。