Detection method

The present invention relates to a method of detecting Hand-Foot-and-Mouth Disease (HMFD) in subjects. In particular, the method relates to detecting promising biomarkers in the saliva of these subjects. In an aspect of the present invention, there is provided a method for detecting HFMD, the method...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	NYO MIN, CHU JANG HANN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention relates to a method of detecting Hand-Foot-and-Mouth Disease (HMFD) in subjects. In particular, the method relates to detecting promising biomarkers in the saliva of these subjects. In an aspect of the present invention, there is provided a method for detecting HFMD, the method comprising determining the presence of a microRNA (miRNA) in a saliva sample, wherein the presenceof the miRNA in the saliva sample is indicative of HFMD. Preferably, the miRNA is any one selected from the group consisting of mir-18b, mir-125a, mir-145, mir-155, mir-221, mir-324, mir- 335 and further comprises mir-23a and mir-142. 本发明涉及一种检测受试者的手足口病(HFMD)的方法。特别地，该方法涉及检测这些受试者的唾液中有前景的生物标志物。在本发明的一个方面，提供了一种用于检测HFMD的方法，该方法包括确定唾液样品中微小RNA(miRNA)的存在，其中唾液样品中miRNA的存在指示HFMD。优选地，miRNA是选自mir-18b、mir-125a、mir-145、mir-155、mir-221、mir-324、mir-335中的任何一种，并且还包含mir-23a和mir-142。