Arylpyrimidine-type pleuromutilin derivative and preparation method and application thereof

The invention relates to pleuromutilin derivatives as shown in a general formula (I), and stereoisomers, pharmaceutically acceptable salts or crystal forms thereof, or pharmaceutical compositions comprising same, preparation methods and intermediates thereof, and applications thereof for preparing a...

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Bibliographische Detailangaben
Hauptverfasser: XIE CHUAN, HE QIAN, YONG CAN, CAO YULONG, ZHANG YUANYUAN, HUANG BENCHENG, YU WANQING
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention relates to pleuromutilin derivatives as shown in a general formula (I), and stereoisomers, pharmaceutically acceptable salts or crystal forms thereof, or pharmaceutical compositions comprising same, preparation methods and intermediates thereof, and applications thereof for preparing antibacterial medicines. The definition of the general formula (I) is consistent with the specification. 本发明涉及一种通式(I)所述的截短侧耳素衍生物及其立体异构体、药学上可接受的盐或晶型,或包含它们的药物组合物,以及它们的制备方法和中间体,以及在用于制备抗菌药物中的用途。通式(I)所述的定义与说明书一致。