Single nucleotide polymorphism (SNP) site of liver injury caused by polygonum multiflorum and application to disease prediction and diagnosis

The invention belongs to the field of molecular biology, and particularly relates to a single nucleotide polymorphism (SNP) site of liver injury caused by polygonum multiflorum and application of theSNP site to disease prediction and diagnosis. The SNP site of the liver injury caused by the polygonu...

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Hauptverfasser:	YANG WANNA, PANG LILI, WANG GUIQIANG, HOU FENGQIN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention belongs to the field of molecular biology, and particularly relates to a single nucleotide polymorphism (SNP) site of liver injury caused by polygonum multiflorum and application of theSNP site to disease prediction and diagnosis. The SNP site of the liver injury caused by the polygonum multiflorum is firstly provided, the SNP site of the liver injury caused by the polygonum multiflorum is located at the 3009th position on a HLA-B gene starting from the 5' end, the base of the SNP site is G, and the site is named rs1055348. The SNP site is mainly mutated from the base T to the base G. 本发明属于分子生物学领域，具体来说，涉及一种由何首乌导致的肝损伤SNP位点，以及该SNP位点在疾病预测与诊断中的应用。本发明首先提供一种由何首乌所致肝损伤的SNP位点，所述何首乌所致肝损伤SNP位点位于HLA-B基因上自5'端开始的第3009位，所述SNP位点碱基为G，所述位点命名为rs1055348。所述SNP位点主要由碱基T突变为碱基G。