PCV2-PRRSV recombinant virus and preparation method, gene, application and vaccine thereof

The invention provides a PCV2-PRRSV recombinant virus and a preparation method, a gene, an application and a vaccine thereof, and relates to the technical field of virus. The recombinant virus expresses a PRRSV antigen with a PCV2 virus as a vector, and has the advantages of simple operation and easy control by using the characteristic that the PCV2 genome is small and capable of rolling circle replication. The PRRSV antigen is selected from polypeptide with good immunogenicity in PRRSV, and the recombinant virus obtained by inserting the PRRSV antigen into the PCV2 virus has dual antigenic characteristics of PRRSV and PCV2, and can make a body produce immune response to PRRSV and PCV2 at the same time. Based on the concept of the invention, the invention also provides a gene mainly composed of a gene sequence encoding PCV2 and a gene sequence encoding the PRRSV antigen, a biomaterial containing the gene, and a vaccine, wherein the vaccine provided by the invention has diimmunogenicityof PRRSV and PCV2, and c