Polysubstituted nitrogenous heterocyclic compound and production method and application thereof

The invention discloses a polysubstituted nitrogenous heterocyclic compound as shown in a formula (III). A production method of the polysubstituted nitrogenous heterocyclic compound as shown in the formula (III) comprises the steps of mixing a compound as shown in a formula (I), a compound as shown...

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Hauptverfasser: PAN ZEXI, CUI DONGMEI, ZHAO WANQIU, ZENG MING
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a polysubstituted nitrogenous heterocyclic compound as shown in a formula (III). A production method of the polysubstituted nitrogenous heterocyclic compound as shown in the formula (III) comprises the steps of mixing a compound as shown in a formula (I), a compound as shown in a formula (II), a metal catalyst, an alkaline substance and an organic solvent, carrying out a stirring reaction at 80-140 DEG C for 5-30 h, and then conducting post-treatment on reaction liquid to obtain the product as shown in the formula (III). The compound as shown in the formula (III) can beapplied to synthesis of a triazine derivative with antibacterial and anti-tumor biological activity. The polysubstituted nitrogenous heterocyclic compound and the production method and application thereof are developed. According to the polysubstituted nitrogenous heterocyclic compound as shown in the formula (III), the production technology has mild reaction conditions, the raw materials are easy to obtain, operation is