Control method for anti-oxidation of vitamin C injection

The invention relates to the technical field of vitamin C injections, and specifically provides a control method for anti-oxidation of a vitamin C injection. The method comprises the following steps:(1) quality control of the raw material medicine vitamin C and auxiliary materials; (2) cleaning and...

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Bibliographische Detailangaben
Hauptverfasser: DONG MINGJIANG, WAN XIANGXIN, LI DONGHONG
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention relates to the technical field of vitamin C injections, and specifically provides a control method for anti-oxidation of a vitamin C injection. The method comprises the following steps:(1) quality control of the raw material medicine vitamin C and auxiliary materials; (2) cleaning and drying of ampoule bottles; (3) preparation: the raw material vitamin C and auxiliary materials areadded according to the prescription dosage to prepare a liquid medicine; (4) fine filtration: filtration is performed through a 0.22 micron microporous membrane cartridge filter; (5) potting; (6) sterilization: the sterilization condition is 100 DEG C and 9 min. After sterilization, spray equipment is turned on to cool the ampoule bottles. The raw material is strictly controlled, and the process is adjusted and optimized. After the vitamin C injection produced by the above control method is detected through an acceleration test and a long-term stability test, various properties all meet the standard requirements, stabi