Synthesis method of mono-sulfhydryl bis-hexadecyl ether polyethylene glycol interchain oligosaccharide glycolipid

The invention discloses a synthesis method of mono-sulfhydryl bis-hexadecyl ether polyethylene glycol interchain oligosaccharide glycolipid. The method is characterized in that 2,3,4,6-O-acetyl-alpha-D-mannopyranose trichloroacetimidate and allyloxy triethylene glycol are used for synthesizing epoxypropyl triethylene glycol acyl mannose in the serial reaction in which chloroperoxybenzoic acid MCPBA and trimethylsilyl trifluoromethanesulfonate TMSOTf are adopted as catalysts; the mannose derivative is sequentially mixed with cetyl alcohol and triphenyl heptadecyl methanesulfonate, and triphenyl-dihexadecyl polyethylene glycol mannose is synthesized by taking sodium hydride as a strong base and adopting boron trifluoride diethyl ether BF3-C2H6O and tetrabutylammonium iodide TABI as catalysts; finally, triphenyl-dihexadecyl polyethylene glycol mannose is mixed with trifluoroacetic acid TFA under the condition of sodium superbase blocks and subjected to a reaction under the catalysis of aphase transfer catalyst b