Eutectic compound formed by lipase inhibitor and hydroxy methylglutaryl coenzyme A reductase inhibitor

The invention provides a eutectic compound formed by a lipase inhibitor and a hydroxy methylglutaryl coenzyme A reductase inhibitor and composition containing the eutectic compound. The eutectic compound is characterized in that the lipase inhibitor is selected from one of orlistat and cetilistat; the hydroxy methylglutaryl coenzyme A reductase inhibitor is selected from one of atorvastatin, rosuvastatin, simvastatin, fluvastatin, pravastatin, lovastatin and pitavastatin or pharmacologically acceptable salts thereof. The eutectic compound can simultaneously have synergistic antibacterial action and synergistic histamine release inhibition function, so that the treatment effect on patients with allergic diseases caused by bacterial infection and the economic characteristics can be improved. 本发明提供了一种由脂肪酶抑制剂与羟甲戊二酰辅酶A还原酶抑制剂构成的共晶复合物以及含有该共晶复合物的组合物，其特征在于，本发明所述的脂肪酶抑制剂是选自奥利司他与西替利司他中的一种；而所述的羟甲戊二酰辅酶A还原酶抑制剂是选自阿托伐他汀、瑞舒伐他汀、辛伐他汀、氟伐他汀、普伐他汀、洛伐他汀与匹伐他汀中的一种或其药学上可接受的盐。本发明所述共晶复合物能同时产生协同的抗菌作用与协同的抑制组胺释放作用，从而能提高细菌感染致过敏性疾病患者治疗的效果与经济学特