Bispecific antibody and its application

The present invention provides a novel antibody and a method of treating cancer. In particular, the invention relates to a bispecific antibody that target CD3 and tumor antigen targets, such as HER2,a preparation method of the antibody, and uses thereof. The invention also relates to a composition c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LUO TONGHUI, ZHANG WENJUN, WEI XUEMEI, CHEN CUIJUAN
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The present invention provides a novel antibody and a method of treating cancer. In particular, the invention relates to a bispecific antibody that target CD3 and tumor antigen targets, such as HER2,a preparation method of the antibody, and uses thereof. The invention also relates to a composition comprising the above antibody and a method of using the antibody to treat cancer. 本发明提供了新的抗体和癌症治疗方法。具体地说,本发明涉及靶向CD3和肿瘤抗原靶点例如HER2的双特异性抗体,所述抗体的制备方法及其用途。本发明还涉及包含上述抗体的组合物以及使用所述抗体治疗癌症的方法。