Daunomycinone intermediate compound

The invention belongs to the field of medicine synthesis and particularly provides a daunomycinone intermediate compound. Daunomycinone can be purely chemically synthesized by adoption of the intermediate compound. By adoption of 2,5-dyhydroxylbenzyl alcohol as a raw material for daunomycinone synth...

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Bibliographische Detailangaben
Hauptverfasser: SHI JIANGHUA, ZHANG GUIMIN, HUO LINGYAN
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention belongs to the field of medicine synthesis and particularly provides a daunomycinone intermediate compound. Daunomycinone can be purely chemically synthesized by adoption of the intermediate compound. By adoption of 2,5-dyhydroxylbenzyl alcohol as a raw material for daunomycinone synthesis, low cost of raw materials, mild reaction conditions, convenience in aftertreatment and high total yield are realized, and a promising industrial application prospect is achieved. 本发明属于医药合成领域,具体提供一种柔红酮中间体化合物,利用该中间体化合物可纯化学合成柔红酮。该路线以2,5-二羟基苄醇为原料合成柔红酮,该路线原料成本低廉,反应条件温和,后处理方便,总收率高,具有较好的工业化应用前景。