Human ScFv single-chain antibody resistant to IL-6 (interleukin-6)

The invention discloses protein of a single-chain antibody resistant to IL-6 (interleukin-6). The single-chain antibody has antigen recognition capability with high specificity, the protein of the single-chain antibody has the specific recognition effect of the antibody, meanwhile, the recognition c...

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1. Verfasser: LYU XINJUN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses protein of a single-chain antibody resistant to IL-6 (interleukin-6). The single-chain antibody has antigen recognition capability with high specificity, the protein of the single-chain antibody has the specific recognition effect of the antibody, meanwhile, the recognition capability can be blocked by a specific receptor, the antibody fusion protein has small molecular weight and can be expressed in a prokaryotic cell expression system, and the production cost of an antibody drug is greatly reduced. 本发明公开了一种抗白介素6的单链抗体的蛋白质,所述单链抗体具有高度特异性的抗原识别能力,所述单链抗体蛋白既具有抗体的特异性识别作用,同时这种识别性又可以被特异性受体阻断,而且该抗体融合蛋白的分子量小,可以在原核细胞表达系统中表达,大大降低了抗体药物的生产成本。