Ethoxy bridged thiazole coumarin compounds and preparation method and application thereof

The invention relates to ethoxy bridged thiazole coumarin compounds and a preparation method and application thereof, and belongs to the technical field of chemical synthesis. The general formula of the ethoxy bridged thiazole coumarin compounds is as shown in formulas I-II, and the formulas are sho...

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Hauptverfasser: ZHOU CHENGHE, GENG RONGXIA, HU CHUNFANG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to ethoxy bridged thiazole coumarin compounds and a preparation method and application thereof, and belongs to the technical field of chemical synthesis. The general formula of the ethoxy bridged thiazole coumarin compounds is as shown in formulas I-II, and the formulas are shown in the description. The compounds have certain inhibitory activity against one or more of gram-positive bacteria, gram-negative bacteria and fungi, and can be used for preparing antibacterial and/or antifungal drugs, thereby having a chance to provide more safe and efficient diversified candidate drugs for clinical antimicrobial treatment, and being conducive to solving clinical treatment problems such as increasingly serious drug resistance, stubborn pathogenic microorganisms, emerging harmful microorganisms and the like. Raw materials for preparation are simple, and cheap and easy to obtain, the synthetic route is short, and the ethoxy bridged thiazole coumarin compounds are of great significance to infection