Alpha-glucosidase inhibitor extracted from Potentilla bifurca var. Humilior R

The invention relates to the technical field of traditional Chinese medicines, in particular to an alpha-glucosidase inhibitor extracted from Potentilla bifurca var. Humilior R. Extraction, column chromatography isolation and glycosidase inhibitory activity verification are performed on the Potentil...

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Bibliographische Detailangaben
Hauptverfasser: QU XUANZHAO, LI CAIMING, TANG XUN, LIU LIKUAN, LI JINPING, ZENG YANG, LONGZHUDUOJIE, YAN PEIYING
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to the technical field of traditional Chinese medicines, in particular to an alpha-glucosidase inhibitor extracted from Potentilla bifurca var. Humilior R. Extraction, column chromatography isolation and glycosidase inhibitory activity verification are performed on the Potentilla bifurca var. Humilior R to obtain the alpha-glucosidase inhibitor. The alpha-glucosidase inhibitor is extracted from natural plant Potentilla bifurca var. Humilior R widely distributed on Qinghai-Tibet Plateau and serves as a monomeric compound, the alpha-glucosidase inhibitor is high in purity and inhibition ratio, an extraction process is simple, convenient and safe, alpha-glucosidase inhibitory activity of the alpha-glucosidase inhibitor is firstly discovered, inhibitory effect is good, a basis can be provided for preparation of novel hypoglycemic drugs, and the alpha-glucosidase inhibitor can serve as a drug for reducing postprandial blood sugar of diabetic patients. 本发明涉及中药技术领域,具体地说是一种从矮生二裂委陵菜中提取的α-葡萄糖苷酶抑制剂