Production method and production module for upstream staged interception of biological macromolecules, and application of method and module in production

The invention provides a production method for staged interception in an upstream production process of biological macromolecules, a production module matched with the method and application of the method/the module in industrial production of polypeptides, fusion proteins and immunoglobulin molecules. The method can effectively improve the efficiency, the yield and the purity of a large-scale recombinant protein upstream process. 本发明提供了一种生物大分子上游生产过程中分阶段截留的生产方法、配合该方法使用的生产模块以及该方法/模块在工业化生产多肽、融合蛋白以及免疫球蛋白分子上的应用。本发明的方法可以有效地实现大规模重组蛋白上游工艺的效率、产量和纯度的提高。