ANTI-CXCR4 ANTIBODIES

The present invention relates to monospecific antibodies against CXCR4 or binding fragments thereof, to the use of such anti-CXCR4 antibodies or binding fragments in treating diseases whose pathogenesis is related to activation of CXCR4, as well as to pharmaceutical compositions comprising such anti...

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Bibliographische Detailangaben
Hauptverfasser: ABBASOVA SVETLANA, KREIMER DAVID, STAUFFER-KELLEHER COLLEEN, KIM ELDAR, MOULON CORINNE, MCALLISTER ANDRES, ULITIN ANDREY, MIKHAYLOV ROMAN, VASILYEVA VIKTORIIA, MIRZABEKOV TAJIB, RIMKEVICH OLGA
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention relates to monospecific antibodies against CXCR4 or binding fragments thereof, to the use of such anti-CXCR4 antibodies or binding fragments in treating diseases whose pathogenesis is related to activation of CXCR4, as well as to pharmaceutical compositions comprising such anti-CXCR4 antibodies or binding fragments. 本发明涉及针对CXCR4的单特异性抗体或其结合片段,涉及此类抗CXCR4抗体或结合片段在治疗发病机理涉及CXCR4的活化的疾病中的用途,以及涉及包含此类抗CXCR4抗体或结合片段的药物组合物。