PROCESS FOR MAKING A COATED DOSAGE FORM

The present invention is directed to a process for making a dosage form comprising at least one pharmaceutically active ingredient, the method comprising the steps of (i) providing a shape of the dosage form comprising at least two powder layers, wherein the first powder layer comprises a surface stabilizing agent and the second powder layer comprises at least one activator and the pharmaceutically active ingredient, wherein the activator has a Q value of less than 75; (ii) applying a radiofrequency energy for a sufficient period of time to the shape of step (i); and (iii) applying heat for asufficient period of time to the shape of step (i). 本发明涉及一种用于制备包含至少一种药物活性成分的剂型的方法，该方法包括以下步骤：(i)提供包括至少两个粉末层的所述剂型的坯，其中第一粉末层包含表面稳定剂，并且第二粉末层包含至少一种活化剂和药物活性成分，其中活化剂的Q值小于75；(ii)对步骤(i)的坯施加足够时间段的射频能量；以及(iii)对步骤(i)的坯施加足够时间段的热量。