2-(morpholin-4-yl)-l,7-naphthyridines

The present invention relates to substituted 2-(morpholin-4-yl)-1,7-naphthyridine compounds of general formula (I) or (lb), to methods of preparing said compounds, to intermediate compounds useful forpreparing said compounds, to pharmaceutical compositions and combinations comprising said compounds...

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Hauptverfasser: BADER BENJAMIN, LIENAU PHILIP, MOOSMAYER DIETER, KOPPITZ MARCUS, VON NUSSBAUM FRANZ, SIEMEISTER GERHARD, EBERSPACHER UWE, EIS KNUT, WORTMANN LARS, LUCKING ULRICH, BONE WILHELM, WENGNER ANTJE MARGRET, GRUDZINSKA-GOEBEL JOANNA, LEFRANC JULIEN, BRIEM HANS, SCHICK HANS
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention relates to substituted 2-(morpholin-4-yl)-1,7-naphthyridine compounds of general formula (I) or (lb), to methods of preparing said compounds, to intermediate compounds useful forpreparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyperproliferative disease as a sole agent or in combination with other active ingredients. 本发明涉及2-(吗啉-4-基)-1,7-萘啶。具体地,本发明涉及通式(I)或(Ib)的取代的2-(吗啉-4-基)-1,7-萘啶化合物,制备所述化合物的方法,可用于制备所述化合物的中间体化合物,包含所述化合物的药物组合物和组合,和所述化合物用于制备治疗或预防疾病的药物组合物的用途,特别是所述化合物作为唯一药剂或与其他活性成分组合用于制备治疗或预防过度增殖性疾病的药物组合物的用途。