Enhanced animal gene vaccine vector

The invention discloses an enhanced animal gene vaccine vector comprising the components by mass: 2.5-4.8 parts of a gene vaccine structural protein, 15.3-27.6 parts of supramolecular hydrogel, 3.4-6.8 parts of a mineral oil adjuvant, 0.5-0.75 part of phosphatase, and a kanamycin resistance gene. Th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: JI PUYU, WEI MAN, JI XINGYU, YAO FENMAO, LI GUOHUI, WANG YANHUI, HAN YUNTAO, LI ZIBO
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses an enhanced animal gene vaccine vector comprising the components by mass: 2.5-4.8 parts of a gene vaccine structural protein, 15.3-27.6 parts of supramolecular hydrogel, 3.4-6.8 parts of a mineral oil adjuvant, 0.5-0.75 part of phosphatase, and a kanamycin resistance gene. The enhanced animal gene vaccine vector can enhance the immunogenicity, enhance the titer of an antibody vaccine and reduce the occurrence of side effects. 本发明公开了一种增强型动物基因疫苗载体,其包括的组分和质量含量为:基因疫苗结构蛋白的质量含量为2.5-4.8份、超分子水凝胶15.3-27.6份、矿物油佐剂3.4-6.8份、磷酸酶0.5-0.75份和卡那霉素抗性基因。本发明的增强型动物基因疫苗载体能够增强免疫原性、增强抗体疫苗的滴度,减少副反应的发生。