Kit and method for detecting genes related to individualized medication for depression

The invention discloses a primer group, a kit and a detection method for detecting genes related to individualized medication for depression. The primer group is selected from nucleotide sequences inSEQ ID NO.1-SEQ ID NO.154. The detection kit covers eight major categories of clinical first-line and...

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Hauptverfasser:	LIU QIAN, DENG MEIYING, XIA HAOQIANG, LI JIEYING, DU ZHIHUI, ZHOU HUANGKAI, CAO ZHIJIA
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention discloses a primer group, a kit and a detection method for detecting genes related to individualized medication for depression. The primer group is selected from nucleotide sequences inSEQ ID NO.1-SEQ ID NO.154. The detection kit covers eight major categories of clinical first-line and second-line antidepressant efficacy-related genes, and relates to drug metabolism, target spots and transporter gene loci, and detection is conducted comprehensively and accurately. Accordingly, aiming at part of patients suffering from treatment-refractory depression, gene detection related to the therapeutic effect of antidepressant synergistic drugs is added, and powerful support is provided for selection of therapeutic schedules of the treatment-refractory depression. 本发明公开了一种用于检测抑郁症个体化用药相关基因的引物组、试剂盒以及检测方法，引物组选自SEQ ID NO.1～SEQ ID NO.154核苷酸序列。本发明的检测试剂盒覆盖临床一线、二线的8大类抗抑郁药物疗效相关的基因，涉及药物代谢、靶点、转运基因位点，检测全面准确；本发明针对部分难治性抑郁症患者增加抗抑郁增效药物疗效相关的基因检测，为难治性抑郁治疗方案的选择提供有力的支持。