Economical synthesis method of 1, 2-dimethyl-1, 4, 5, 6-tetrahydro pyrimidine
The invention provides an economical synthesis method of 1, 2-dimethyl-1, 4, 5, 6-tetrahydro pyrimidine. According to the economical synthesis method, thioacetamide or hydrogen sulfide are added as catalysts, so that reaction time of N-methyl propane diamine with acetonitrile is shortened greatly, h...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention provides an economical synthesis method of 1, 2-dimethyl-1, 4, 5, 6-tetrahydro pyrimidine. According to the economical synthesis method, thioacetamide or hydrogen sulfide are added as catalysts, so that reaction time of N-methyl propane diamine with acetonitrile is shortened greatly, high yield is achieved in a relatively short reaction time period, and reaction economical benefit isincreased greatly.
本发明提供的1,2-二甲基-1,4,5,6-四氢嘧啶合成方法,通过添加硫代乙酰胺或者硫化氢作为催化剂,大大缩短了N-甲基丙二胺与乙腈的反应时间,在较短的反应时间内得到了高收率,极大的提高了反应的经济性。 |
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