Liquid aerosol lung delivery immunity mouse model of botulinum neurotoxin AHc vaccine

The invention discloses a liquid aerosol lung delivery immunity mouse model of a botulinum neurotoxin AHc vaccine. The effective component of an A type botulinum neurotoxin vaccine provided by the invention is aerosol of a specific solution, wherein the specific solution contains specific protein and a mucosal immunity adjuvant, the specific protein is AHc protein or fusion protein having the AHcprotein, the mass compounding ratio of the specific protein to the mucosal immunity adjuvant is 1 to (0.5-1.5), and the AHc protein is the protein as shown in a sequence 1 of a sequence table. A recombinant protein AHc subunit vaccine is selected, a lung delivery immunity manner is used for the first time, and in vivo efficacy and in vitro efficacy of the AHc subunit vaccine are researched. The vaccine can protect a mouse from being attacked by a deadly A type botulinum neurotoxin. Lung delivery is performed through trachea, so that samples can directly reach the lung target organ, the effectsare direct, medicines are