Di-benzofuran-benzimidazole salt compound with anti-tumor activity and preparation method thereof

The invention belongs to the technical field of medicines and relates to a di-benzofuran-benzimidazole salt compound with a novel structure and obvious anti-tumor activity and a preparation method thereof. In the invention, active molecules are designed on a basis of a di-benzofuran compound and a benzimidazole compound that have good activity; a synthesis method is efficient and concise; the provided di-benzofuran-benzimidazole salt compound with the structure shown as the formula I has obviousin-vitrotumor growth inhibition activity for five human cancer cells (leukemia, liver cancer, lung cancer, breast cancer and conlon cancer cells),and the inhibition activity of the di-benzofuran-benzimidazole salt compound is prior to that of an anti-cancer drug cisplatin DDP (didecyl phthalate). Therefore, the di-benzofuran-benzimidazole salt compound has the potential of becoming an anti-tumor drug. 本发明属于医药技术领域，涉及一种结构新颖、抗肿瘤活性显著的双苯并呋喃-苯并咪唑盐类化合物及其制备方法。本发明基于具有良好活性的双苯并呋喃化合物和苯并咪唑化合物进行活性分子的设计，合成方法高效简洁，所提供的具有式Ⅰ所示结构的双苯并呋喃-苯并