Pharmaceutical application of 3-trametenolic acid B methyl cyanide

The invention provides application of 3-trametenolic acid B methyl cyanide in preparing anti-hepatitis B virus drugs, and further relates to application of the 3-trametenolic acid B methyl cyanide inpreparing drugs inhibiting HBsAg secretion of a human hepatocellular carcinoma HepG2/2.2.15 cell stra...

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Bibliographische Detailangaben
Hauptverfasser: WANG YUNZHI, LI LI'E, LUO FAJUN, DENG GAIGAI, WAN YULIAN, HUANG NIANYU, SHI FEIFAN, HE HAIBO
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides application of 3-trametenolic acid B methyl cyanide in preparing anti-hepatitis B virus drugs, and further relates to application of the 3-trametenolic acid B methyl cyanide inpreparing drugs inhibiting HBsAg secretion of a human hepatocellular carcinoma HepG2/2.2.15 cell strain, or application of 3-trametenolic acid B methyl cyanide in preparing drugs expressing hepatoma carcinoma cell HBx expression. The 3-trametenolic acid B methyl cyanide has positive effects on preventing hepatitis b virus infection, treating hepatitis B infection, preventing hepatocellular carcinoma, treating hepatitis B related hepatocellular carcinoma and preventing relapse in the whole process of lesions. The great significance on solving the technical problem of clinically treating hepatitis B infection, and especially the hepatitis B related hepatocellular carcinoma is achieved. 本发明提供一种3-氢化松苓酸B氰甲酯在制备抗乙肝病毒的药物中的应用。进一步为所述的3-氢化松苓酸B氰甲酯在制备抑制人肝癌HepG2/2.2.15细胞株的HBsAg分泌的药物上的应用。或3-氢化松苓酸B氰甲酯在制备表达肝癌细胞HBx表达的药物上的应用。本发明所述的3