Bacteriocin produced by Bacillus coagulans and application thereof

The invention provides a bacteriocin produced by Bacillus coagulans and an application thereof, which belong to the field of microorganisms, the bacteriocin is extracted from of Bacillus coagulans with a preservation number of CGMCC NO. 9951, and can tolerate simulated gastric acid and simulate bile salt environment; has significant probioticity and can effectively inhibit growth and reproductionof Escherichia coli, Pastevula mulfocida, salmonella typhi, Salmonella, Shigella dysenteriae, Vibrio alginolyticus, Aeromonas hydrophila, and vibrio parahaemolyticus; and the bacteriocin has good stability and good antibacterial effect. The bacteriocin and bacteriocin-producing Bacillus coagulans can be used in the fields of prevention and control of poultry and aquatic diseases. 本发明提供了一种凝结芽孢杆菌产的细菌素及其应用，属于微生物领域，所述细菌素从保藏编号为CGMCC NO.9951的凝结芽孢杆菌中提取获得，可以耐受模拟胃酸、模拟胆盐环境；具有显著的益生性，可有效抑制大肠杆菌、禽巴氏杆菌、伤寒沙门氏菌、沙门氏菌、志贺氏杆菌、溶藻弧菌、嗜水气单胞菌、副溶血弧菌的生长繁殖；细菌素稳定性好，抑菌效果好，该细菌素及产细菌素的凝结芽孢杆菌可以应用于禽畜和水产疾病防治领域。