SUBSTITUTED HYDANTOIN AND THIOHYDANTOIN DERIVATIVES AS ANDROGEN RECEPTOR ANTAGONISTS

Disclosed are compounds, compositions and methods for treating of disorders that are affected by the antagonism of one or more androgen receptor types. Such compounds are represented by Formula (I), wherein R1, R2a, R,2b, Z, X and Y are defined herein and G is selected (g1) or (g2). 本发明公开了一种用于治疗紊乱的化...

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Hauptverfasser:	PANDE VINEET, HICKSON IAN, TRABALON ESCOLAR LUIS B, BIGNAN GILLES C, MEERPOEL LIEVEN, ZHANG ZHUMING, CONNOLLY PETER J, ROCOBOY CHRISTIAN, BRANCH JONATHAN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Disclosed are compounds, compositions and methods for treating of disorders that are affected by the antagonism of one or more androgen receptor types. Such compounds are represented by Formula (I), wherein R1, R2a, R,2b, Z, X and Y are defined herein and G is selected (g1) or (g2). 本发明公开了一种用于治疗紊乱的化合物、组合物和方法，所述紊乱受一种或多种雄性激素受体类型拮抗作用的影响。此类化合物由下式(I)表示：其中R--、R--、R--、Z、X和Y在本文中定义，并且G选自(g1)或(g2)。