Environment-friendly preparation method of N,N-dimethylformamide dimethylacetal

The invention relates to the field of organic synthesis, in particular to an environment-friendly preparation method of N,N-dimethylformamide dimethylacetal. The preparation method comprises the following steps that sodium methoxide and chloroform generates dimethoxy chloromethane under the action of a catalyst; the dimethoxy chloromethane obtained in the last step is reacted with dimethylamine toobtain the N,N-dimethylformamide dimethylacetal. The preparation method has the advantages that hypertoxic dimethyl sulfate is prevented from being used; only through simple treatment, sodium chloride generated by the reactions can be used as a byproduct for sales, the yield of solid wastes can be reduced, and the economic benefits of the product can be increased. 本发明涉及有机合成领域，尤其涉及一种环境友好的N,N-二甲基甲酰胺二甲缩醛制备方法，包括如下步骤：甲醇钠与氯仿在催化剂作用下生成二甲氧基氯甲烷；上述步骤得到的二甲氧基氯甲烷与二甲胺反应得到N,N-二甲基甲酰胺二甲缩醛。本发明优势在于：避免使用剧毒的硫酸二甲酯；反应产生的氯化钠经过简单处理即可作为副产品外售，既可以减少固废的产生量，又可增加产品的经济效益。