Traditional Chinese medicine composition for regulating reverse cholesterol transport and application of composition
The invention relates to a traditional Chinese medicine composition for regulating reverse cholesterol transport. The traditional Chinese medicine composition is prepared from, by weight, 30 parts ofraw radix astragali, 20 parts of radix salviae miltiorrhizae, 15 parts of trichosanthes kirilowii max...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention relates to a traditional Chinese medicine composition for regulating reverse cholesterol transport. The traditional Chinese medicine composition is prepared from, by weight, 30 parts ofraw radix astragali, 20 parts of radix salviae miltiorrhizae, 15 parts of trichosanthes kirilowii maxim and 12 parts of leeches. The invention also provides application of the traditional Chinese medicine composition. The traditional Chinese medicine composition directly acts on an LXRalpha-SREBP1-ABCA1/G1 signal channel in arterial blood vessel macrophage, and further influences and reverses cholesterol efflux on the surface of the macrophage, so that the function of preventing generation and development of ASCVD is achieved. Clinical experiments verify that the traditional Chinese medicine composition can inhibit formation of plaques, improve the properties of plaques and improve the blood lipid condition of a patient, the side effect on the liver and kidneys is small, the safety is high, and atherosclerosis can |
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