Preparation method of moisture-resistant absorbable disintegrating traditional Chinese medicine hard capsule material
The invention relates to a preparation method of a moisture-resistant absorbable disintegrating traditional Chinese medicine hard capsule material, and belongs to the technical field of pharmaceuticalmaterials. The technical scheme includes that dimethyl aminopyridine induced lactic acid and mandeli...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention relates to a preparation method of a moisture-resistant absorbable disintegrating traditional Chinese medicine hard capsule material, and belongs to the technical field of pharmaceuticalmaterials. The technical scheme includes that dimethyl aminopyridine induced lactic acid and mandelic acid are copolymerized in a ring-opening manner to obtain a polylactic acid-polymandelic acid copolymer, after polymandelic acid is introduced into a polylactic acid main chain, a coating material is prepared, the structural strength and the moisture resistance of the material are effectively improved by coating of the coating material, the dissociation process of polymer chain links is continuously performed under the simultaneous action of surfactants and plasticizers, finally, a whole molecule escapes from a particle to form aqueous dispersion, balance between the structural performance and the disintegration of the material is effectively improved, peach gum particles are adhered anddispersed in the preparati |
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