COMPOSITIONS COMPRISING 5-CHOLESTEN-3, 25-DIOL, 3-SULFATE (25HC3S) OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND AT LEAST ONE CYCLIC OLIGOSACCHARIDE

COMPOSITIONS COMPRISING 5-CHOLESTEN-3, 25-DIOL, 3-SULFATE (25HC3S) OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND AT LEAST ONE CYCLIC OLIGOSACCHARIDE

Compositions comprising 5-cholesten-3, 25-diol, 3-sulfate (25HC3S) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide, e.g., a cyclodextrin (CD), are provided. The compositions may be used to prevent and/or treat a variety of diseases and conditions, including organ...

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Hauptverfasser: KIM MEEJ, MIKSZTAL ANDREW R, WU HONGWEI, LEE MIN L, NING YANXIA, XU LEYUAN, KIM JIN KOUNG, LIN WEIQI, TAMRAZ WILMA, REN SHUNLIN
Format: Patent
Sprache:chi ; eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
STEROIDS
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Zusammenfassung:Compositions comprising 5-cholesten-3, 25-diol, 3-sulfate (25HC3S) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide, e.g., a cyclodextrin (CD), are provided. The compositions may be used to prevent and/or treat a variety of diseases and conditions, including organ failure (e.g. acute liver failure), high cholesterol/high lipids, and various inflammatory diseasesand conditions. 提供了组合物，其包含5-胆甾烯-3,25-二醇,3-硫酸酯(25HC3S)或其药学上可接受的盐和至少一种环状寡糖，例如，环糊精(CD)。所述组合物可以用于预防和/或治疗多种疾病和病症，包括器官衰竭(例如急性肝衰竭)、高胆固醇/高脂质和各种炎性疾病和病症。