Vaccine formulation and method for preventing iridoviral disease in fish

The present invention provides a method for controlling more effective iridovirus infection diseases in fishes such as the genus Oplegnathus. The present invention provides a vaccine formulation containing inactivated iridovirus as an antigen and requiring 107.0 TCID 50 or more per dose for the iridovirus infectious disease in fish and the like. Through inactivated iridovirus as an antigen and administering 107.0 TCID 50 or more per dose, even though sea bream species or the like which has been considered as a vaccine in the past can be effectively avoided. The concentration of the iridovirusin the vaccine preparation can be increased to 107.0 TCID 50 or more per dose by including a concentrated solution of a culture supernatant obtained when the iridovirus is proliferated in the culturedcells, or the culture supernatant, virus-infected cultured cells, or the like. 本发明提供针对石鲷属鱼种(genus Oplegnathus)等的更有效的鱼类的虹彩病毒(iridovirus)感染性疾病的防除方法。提供含有非活化的虹彩病毒作为抗原且每次给要10TCID以上的针对鱼类的虹彩病毒感染性疾病的疫苗制剂等。通过包含非活化的虹彩病毒作为抗原且每次给要10TCID以